Nequinate
Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections. Nequinate inhibits xanthine oxidoreductase (XOD) activity.
For research use only. We do not sell to patients.
- CAS No.: 13997-19-8
- Formula: C22H23NO4
- Molecular Weight:365.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Coccidia |
Xanthine oxidase (XOD) is a successful and safe drug target for lowering lower serum urate (sUA) levels , it plays an important role in the catabolism of purineNequinate shows an inhibition of 12.0% to inhibit XOD activities[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 13997-19-8
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Molecular Weight 365.42
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Formula C22H23NO4
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SMILES
O=C(C1=CNC2=C(C=C(CCCC)C(OCC3=CC=CC=C3)=C2)C1=O)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. D K McLoughlin, et al.Efficacy of Nequinate Against Thirteen Strains of Eimeria Tenella and the Development of a Nequinate-Resistant Strain.Avian Dis. Oct-Dec 1973;17(4):717-21. [Content Brief]
[2]. Yanfen Niu, et al. Old Drug, New Indication: Olsalazine Sodium Reduced Serum Uric Acid Levels in Mice via Inhibiting Xanthine Oxidoreductase Activity. J Pharmacol Sci. 2017 Nov;135(3):114-120. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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