A 844606
A 844606 is a highly potent and selective α4β2 nAChR agonist. A 844606 can be used in the study of schizophrenia, Huntington's disease, Alzheimer's disease, and Parkinson's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 861119-08-6
- 分子式: C20H20N2O2
- 分子量:320.39
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
>100 μM
Compound: 52
|
Agonist activity at human recombinant alpha3beta4 nAChR in HEK293 cells by FLIPR assay
Agonist activity at human recombinant alpha3beta4 nAChR in HEK293 cells by FLIPR assay
|
[PMID: 22281189] |
| HEK293 | EC50 |
>100 μM
Compound: 52
|
Agonist activity at human recombinant alpha4beta2 nAChR in HEK293 cells by FLIPR assay
Agonist activity at human recombinant alpha4beta2 nAChR in HEK293 cells by FLIPR assay
|
[PMID: 22281189] |
| Oocyte | EC50 |
2.2 μM
Compound: 52
|
Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes by patch clamp assay
Agonist activity at human recombinant alpha7 nAChR expressed in xenopus oocytes by patch clamp assay
|
[PMID: 22281189] |
化学情報
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CAS 番号 861119-08-6
-
分子量 320.39
-
分子式 C20H20N2O2
-
SMILES
O=C1C2=C(OC3=CC=C(N4CC5CN(CC5C4)C)C=C31)C=CC=C2
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)