AVID100 Antibody
AVID100 (MAB100) Antibody is a monoclonal antibody inhibitor targeting EGFR, which can be used to synthesize a novel antibody-drug conjugate (ADC) molecule AVID100. AVID100 Antibody is applicable to relevant research on breast cancer, head and neck cancer, and lung cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
EGFR アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
Species Reactivity
Human
体外実験
AVID100 Antibody (MAB100) binds EGFR with an affinity of approximately 2 nM, acts as a full EGFR antagonist that blocks downstream signaling, and competes with EGF for EGFR binding[1].
AVID100 induces apoptosis and potent cytotoxicity (with IC50 values correlating with EGFR expression) in MDA-MB-468, H292, and FaDu cancer cells, but does not increase cytotoxicity or apoptosis in normal keratinocytes relative to unconjugated MAB100[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
遺伝子ID
アクセッション番号
Target
ERBB1/EGFR/HER1
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
-
Product Image
アプリケーション
ELISA, FACS, Functional assay
化学情報
-
SMILES
[AVID100 Antibody]
-
別名
MAB100 Antibody
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
AVID100 Antibody 関連分類
HY-P991967 関連分類
Powered by Bioz