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United States

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製品番号: HY-N21864

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Cathayanon J

Cathayanon J is a flavanone natural product with 2R configuration, which is found in the stem bark of Morus cathayana. Cathayanon J exhibits weak cytotoxicity against A549, Bel 7402, BGC-823, HCT-8 and A2780 human cancer cells, with IC₅₀ values of 4.67, 5.95, 6.70, 5.86 and 5.79 μg/mL, respectively. Cathayanon J can be used in cancer-related research.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1303438-53-0
分子式: C₃₀H₃₆O₅
分子量:476.60

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Cathayanon J 構造式

CAS 番号: 1303438-53-0

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC50	4.67 μg/mL	Cytotoxicity against human lung carcinoma A549 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human lung carcinoma A549 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817
Bel-7402	IC50	5.95 μg/mL	Cytotoxicity against human liver carcinoma Bel7402 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human liver carcinoma Bel7402 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817
BGC-823	IC50	6.70 μg/mL	Cytotoxicity against human stomach carcinoma BGC-823 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human stomach carcinoma BGC-823 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817
HCT-8	IC50	5.86 μg/mL	Cytotoxicity against human colon carcinoma HCT-8 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human colon carcinoma HCT-8 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817
A2780	IC50	5.79 μg/mL	Cytotoxicity against human ovarian carcinoma A2780 cells assessed by MTT assay following 4-day incubation. Cytotoxicity against human ovarian carcinoma A2780 cells assessed by MTT assay following 4-day incubation.	10286020.2010.489817

体外実験

Cathayanon J (0.1-10.0 μg/mL; 4 days) exhibits cytotoxicity against human cancer cell lines A549, Bel 7402, BGC-823, HCT-8 and A2780, with IC₅₀ values of 4.67, 5.95, 6.70, 5.86 and 5.79 μg/mL, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

human lung carcinoma (A549), human liver carcinoma (Bel7402), human stomach carcinoma (BGC-823), human colon carcinoma (HCT-8), human ovarian carcinoma (A2780)
Concentration:

0.1, 1.0, 10.0 μg/mL
Incubation Time:

4 days
Result:

Exhibited weak cytotoxic activity against human lung carcinoma (A549) cell line with an IC₅₀ value of 4.67 μg/mL.
Exhibited weak cytotoxic activity against human liver carcinoma (Bel7402) cell line with an IC₅₀ value of 5.95 μg/mL.
Exhibited weak cytotoxic activity against human stomach carcinoma (BGC-823) cell line with an IC₅₀ value of 6.70 μg/mL.
Exhibited weak cytotoxic activity against human colon carcinoma (HCT-8) cell line with an IC₅₀ value of 5.86 μg/mL.
Exhibited weak cytotoxic activity against human ovarian carcinoma (A2780) cell line with an IC₅₀ value of 5.79 μg/mL.

化学情報

CAS 番号 1303438-53-0
分子量 476.60
分子式 C₃₀H₃₆O₅
SMILES

O=C1C2=C(O)C=C(O)C=C2O[C@@H](C3=CC(C/C=C(C)/CC/C=C(C)\C)=C(C(C/C=C(C)\C)=C3)O)C1
Structure Classification
- Flavonoids
- Flavonones
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Ni G, et al. Chemical constituents of the stem bark of Morus cathayana. Journal of Asian Natural Products Research. 2010;12(6):505-515.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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分子量分子量

希釈計算機

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濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

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How should lyophilized recombinant proteins be reconstituted and stored?

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100 mg

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