DMPE-PEG5000-Mal
DMPE-PEG5000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
生物活性
The structure of DMPE-PEG-Mal comprises three key components that work synergistically:
DMPE: Acts as a hydrophobic anchor, securely embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chains: Act as hydrophilic spacers, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
Maleimide: A reaction interface located at the end of the PEG chain, it can undergo a specific Michael addition reaction with biomolecules containing thiol groups (-SH), such as peptides, antibodies, and aptamers, achieving targeting or tracking functions.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
CCCCCCCCCCCCCC(OC[C@@H](OC(CCCCCCCCCCCCC)=O)COP(OCCNC(OCCNC(CCN1C(C=CC1=O)=O)=O)=O)(O)=O)=O.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
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