Drimenal
Drimenal is a pimarane-type natural sesquiterpene with antifungal activity. Drimenal inhibits the growth of yeasts and dermatophytes. Drimenal can be used for the development of pesticide candidates and in research related to fungal infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 105426-71-9
- 分子式: C15H24O
- 分子量:220.35
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
Drimenal-derived chiral oxazinone derivatives exhibit potent antifungal activity against Botrytis cinerea and antibacterial activity against Bacillus subtilis and Ralstonia solanacearum, with improved efficacy over the parent compound and positive controls streptomycin sulfate[1].
Drimenal exhibits moderate fungicidal antifungal activity against Candida albicans ATCC 10231, Saccharomyces cerevisiae ATCC 9763, Cryptococcus neoformans ATCC 32264, Microsporum gypseum CCC 115, Trichophyton rubrum CCC 113, and Trichophyton mentagrophytes ATCC 9972, with MIC100 values ranging from 31.2 to 125 µg/mL and MIC50 values of 62.5 µg/mL against both C. albicans and C. neoformans[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 105426-71-9
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分子量 220.35
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分子式 C15H24O
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SMILES
C[C@@]12[C@](CC=C([C@@H]2C=O)C)([H])C(C)(CCC1)C
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Li D, et al. Synthesis and bio-inspired optimization of drimenal: Discovery of chiral drimane fused oxazinones as promising antifungal and antibacterial candidates. Eur J Med Chem. 2018;143:558-567. [Content Brief]
[2]. Derita M, et al. Structural requirements for the antifungal activities of natural drimane sesquiterpenes and analogues, supported by conformational and electronic studies. Molecules. 2013;18(2):2029-2051. Published 2013 Feb 5. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Drimenal 関連分類
HY-N19881 関連分類
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