Eganelisib (Standard)
Eganelisib (Standard) is the analytical standard of Eganelisib (HY-100716). This product is intended for research and analytical applications. Eganelisib (IPI549) is a potent and selective PI3Kγ inhibitor with an IC50 of 16 nM. Eganelisib shows >100-fold selectivity over other lipid and protein kinases.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98%
- CAS 番号: 1693758-51-8
- 分子式: C30H24N8O2
- 分子量:528.56
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
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HY-100716
EganelisibPI3Kγ Inhibitor -
HY-15244
AlpelisibPI3Kα Inhibitor -
HY-102031
LinperlisibPI3Kδ Inhibitor -
HY-12644
AcalisibPI3K Inhibitor -
HY-101562
InavolisibPI3Kα Inhibitor -
HY-12869
AZD-8835PI3Kα/δ Inhibitor -
HY-70063
BuparlisibPI3K Inhibitor -
HY-109068
ParsaclisibPI3Kδ Inhibitor -
HY-17044
DuvelisibPI3Kδ Inhibitor -
HY-101272
GDC-0326PI3Kα Inhibitor -
HY-13898
TaselisibPIK3CA Inhibitor -
HY-12285
Serabelisibp110α Inhibitor
Product Information
説明
アプリケーション
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 1693758-51-8
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分子量 528.56
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分子式 C30H24N8O2
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SMILES
O=C(C1=C2N=CC=CN2N=C1N)N[C@H](C3=CC4=C(C(N3C5=CC=CC=C5)=O)C(C#CC6=CN(C)N=C6)=CC=C4)C
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別名
IPI-549 (Standard)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Evans CA, et al. Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate. ACS Med Chem Lett. 2016 Jul 22;7(9):862-7. [Content Brief]
[2]. De Henau O, et al. Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells. Nature. 2016 Nov 17;539(7629):443-447. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Eganelisib (Standard) 関連分類
HY-100716R 関連分類
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