p53 Activator 5
Based on 1 Customer Validation
p53 Activator 5 (compound 134A) is a potent p53 activator with a SC150 value of <0.05 mM. p53 Activator 5 can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA. p53 Activator 5 shows anti-tumor activity. p53 Activator 5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2636840-37-2
- 分子式: C29H32F6N4O
- 分子量:566.58
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保管条件:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 2636840-37-2
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性状 Solid
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分子量 566.58
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分子式 C29H32F6N4O
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Color Brown to reddish brown
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SMILES
COC1=CC(C(F)(F)F)=CC=C1NCC#CC2=CC3=C(C=CC=C3N[C@@H](CC4)CC[C@H]4N(C)C)N2CC(F)(F)F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (176.50 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7650 mL | 8.8249 mL | 17.6498 mL | 44.1244 mL |
| 5 mM | 0.3530 mL | 1.7650 mL | 3.5300 mL | 8.8249 mL | |
| 10 mM | 0.1765 mL | 0.8825 mL | 1.7650 mL | 4.4124 mL | |
| 15 mM | 0.1177 mL | 0.5883 mL | 1.1767 mL | 2.9416 mL | |
| 20 mM | 0.0882 mL | 0.4412 mL | 0.8825 mL | 2.2062 mL | |
| 25 mM | 0.0706 mL | 0.3530 mL | 0.7060 mL | 1.7650 mL | |
| 30 mM | 0.0588 mL | 0.2942 mL | 0.5883 mL | 1.4708 mL | |
| 40 mM | 0.0441 mL | 0.2206 mL | 0.4412 mL | 1.1031 mL | |
| 50 mM | 0.0353 mL | 0.1765 mL | 0.3530 mL | 0.8825 mL | |
| 60 mM | 0.0294 mL | 0.1471 mL | 0.2942 mL | 0.7354 mL | |
| 80 mM | 0.0221 mL | 0.1103 mL | 0.2206 mL | 0.5516 mL | |
| 100 mM | 0.0176 mL | 0.0882 mL | 0.1765 mL | 0.4412 mL |
p53 Activator 5 関連分類
HY-148404 関連分類
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