12a-Hydroxydalpanol
12a-Hydroxydalpanol is a rotenoid cytotoxic agent found in Amorpha fruticosa. 12a-Hydroxydalpanol exerts cytotoxic effects by inhibiting tumor cell proliferation. 12a-Hydroxydalpanol is promising for research of cancers.
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- CAS No.: 85042-77-9
- 화학식: C23H24O8
- 분자량:428.43
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | ED50 |
9.28 μg/mL
Compound: 8
|
Cytotoxicity against human A549 cells
Cytotoxicity against human A549 cells
|
[PMID: 8326318] |
| HCT-8 | ED50 |
0.56 μg/mL
Compound: 8
|
Cytotoxicity against human HCT8 cells
Cytotoxicity against human HCT8 cells
|
[PMID: 8326318] |
| KB | ED50 |
3.67 μg/mL
Compound: 8
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 8326318] |
| P388 | ED50 |
0.59 μg/mL
Compound: 8
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 8326318] |
| RPMI-7951 | ED50 |
0.73 μg/mL
Compound: 8
|
Cytotoxicity against human RPMI7951 cells
Cytotoxicity against human RPMI7951 cells
|
[PMID: 8326318] |
| TE-671 | ED50 |
0.12 μg/mL
Compound: 8
|
Cytotoxicity against human TE671 cells
Cytotoxicity against human TE671 cells
|
[PMID: 8326318] |
Chemical Information
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CAS No. 85042-77-9
-
분자량 428.43
-
화학식 C23H24O8
-
SMILES
O[C@@]1([C@](CO2)([H])OC3=C(C[C@@H]4C(C)(O)C)C(O4)=CC=C3C1=O)C(C2=C5)=CC(OC)=C5OC
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)