Antibacterial agent 117
Based on 1 Customer Validation
Antibacterial agent 117, triazole derivative, is an antibacterial agent. Antibacterial agent 117 has against R. prowazekii MetAP1 (RpMetAP1) activity with an IC50 value of 15 μM. Antibacterial agent 117 also inhibits rickettsial growth and can be used for the research of infection.
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- Purity : 98.01%
- CAS No.: 341944-06-7
- 화학식: C9H9ClN4S
- 분자량:240.71
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
IC50: 15 μM (RpMetAP1)[1]
In Vitro
Antibacterial agent 117 can inhibit RpMetAP1 with an IC50 value of 15 μM[1].
Antibacterial agent 117 (0.3 μM, 3 μM, 30 μM and 300 μM) stimulates endothelial cell (EC) metabolism and also inhibits rickettsial growth[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 341944-06-7
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Appearance Solid
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분자량 240.71
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화학식 C9H9ClN4S
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Color White to off-white
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SMILES
NC1=NNC(SCC2=CC=CC=C2Cl)=N1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
DMSO : 100 mg/mL (415.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (281 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1544 mL | 20.7719 mL | 41.5438 mL | 103.8594 mL |
| 5 mM | 0.8309 mL | 4.1544 mL | 8.3088 mL | 20.7719 mL | |
| 10 mM | 0.4154 mL | 2.0772 mL | 4.1544 mL | 10.3859 mL | |
| 15 mM | 0.2770 mL | 1.3848 mL | 2.7696 mL | 6.9240 mL | |
| 20 mM | 0.2077 mL | 1.0386 mL | 2.0772 mL | 5.1930 mL | |
| 25 mM | 0.1662 mL | 0.8309 mL | 1.6618 mL | 4.1544 mL | |
| 30 mM | 0.1385 mL | 0.6924 mL | 1.3848 mL | 3.4620 mL | |
| 40 mM | 0.1039 mL | 0.5193 mL | 1.0386 mL | 2.5965 mL | |
| 50 mM | 0.0831 mL | 0.4154 mL | 0.8309 mL | 2.0772 mL | |
| 60 mM | 0.0692 mL | 0.3462 mL | 0.6924 mL | 1.7310 mL | |
| 80 mM | 0.0519 mL | 0.2596 mL | 0.5193 mL | 1.2982 mL | |
| 100 mM | 0.0415 mL | 0.2077 mL | 0.4154 mL | 1.0386 mL |
Antibacterial agent 117 Related Classifications
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