Desamino lenalidomide-Pip-azetidine hydrochloride
Desamino lenalidomide-Pip-azetidine hydrochloride is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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- CAS No.: 2759147-68-5
- 화학식: C20H25ClN4O3
- 분자량:404.89
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
제품 설명
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2759147-68-5
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분자량 404.89
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화학식 C20H25ClN4O3
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SMILES
O=C1NC(C(CC1)N2C(C3=CC=C(N4CCC5(CC4)CNC5)C=C3C2)=O)=O.Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)