DMG-PEG1000-DBCO
DMG-PEG1000-DBCO is a conjugate composed of dimyristic glycerol (DMG), a PEG chain, and a terminal dibenzocyclooctylene (DBCO). DMG-PEG1000-DBCO combines the membrane compatibility of phospholipids with the high reactivity of the DBCO group in copper-free click chemistry, making it suitable for research in biomaterial construction and drug delivery.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
The structure of DMG-PEG-DBCO comprises three key components that work synergistically:
DMG: Acts as a hydrophobic anchor, securely embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing nonspecific adsorption and immune system clearance, thus prolonging the carrier's circulation time in vivo.
DBCO group: A highly reactive cycloalkyne structure capable of undergoing copper-free click chemistry (azido-alkyne cycloaddition) with molecules containing an azide group (-N3).
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
O=C(CCCCCCCCCCCCC)OC(COC(CCCCCCCCCCCCC)=O)COCCOCCNC(CCC(N1C2=C(C#CC3=C(C1)C=CC=C3)C=CC=C2)=O)=O.[n]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DMG-PEG1000-DBCO Related Classifications
HY-183195 Related Classifications
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