Lipid DBCO

Lipid DBCO (17):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

DSPE-PEG2000-DBCO		99.90%
DSPE-PEG2000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery. DSPE-PEG2000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

DSPE-PEG3400-DBCO sodium		99.63%
DSPE-PEG3400-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-DBCO sodium can be used in drug delivery research.

HY-W440835E

DSPE-PEG5000-DBCO
DSPE-PEG5000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery. DSPE-PEG5000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

DSPE-PEG5000-DBCO sodium
DSPE-PEG5000-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG5000-DBCO sodium can be used in drug delivery research.

DSPE-PEG-DBCO ammonium	2052955-83-4	99.90%
DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research.

Oleic-DBCO	2279951-78-7	98.0%
Oleic-DBCO is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. Oleic-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

DSPE-PEG4-DBCO	2112738-14-2
DSPE-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DSPE-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

DSPE-PEG46-DBCO
DSPE-PEG46-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DSPE-PEG46-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

DSPE-PEG36-DBCO
DSPE-PEG36-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DSPE-PEG36-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

DSPE-PEG8 DBCO	3091879-24-9
DSPE-PEG8-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DSPE-PEG8-DBCO can be used to prepare lipid nanoparticles for drug delivery.

HY-W440835C

DSPE-PEG1000-DBCO
DSPE-PEG1000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery. DSPE-PEG1000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440835A

DSPE-PEG400-DBCO
DSPE-PEG400-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery. DSPE-PEG400-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440835H

DSPE-PEG10000-DBCO
DSPE-PEG10000-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery. DSPE-PEG10000-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440835B

DSPE-PEG600-DBCO
DSPE-PEG600-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery. DSPE-PEG600-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440835D

DSPE-PEG3400-DBCO
DSPE-PEG3400-DBCO is a phospholipid-PEG polymer that can be used to form micelles as lipid nanoparticles for drug delivery. DSPE-PEG3400-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-W440881A

DSPE-PEG3400-C2-DBCO sodium
DSPE-PEG3400-C2-DBCO sodium is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DSPE-PEG3400-C2-DBCO sodium can be used in drug delivery research.

DOPE-PEG5000-DBCO
DOPE-PEG5000-DBCO is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. DOPE-PEG5000-DBCO can be used in drug delivery research.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01
Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

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