DSPE-PEG2000-Glucose
DSPE-PEG2000-Glucose is a conjugate composed of DSPE, a PEG chain, and terminal glucose. DSPE-PEG2000-Glucose combines the membrane compatibility of phospholipids with glucose as an active site for sugar recognition or subsequent coupling reactions, making it suitable for research in biomaterial construction and drug delivery.
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- 분자량:2000 (Average)
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
The structure of DSPE-PEG-Glucose comprises three key components that work synergistically:
DSPE: Acts as a hydrophobic anchor, securely embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chain: Acts as a hydrophilic spacer, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system clearance, and prolonging the carrier's circulation time in vivo.
Glucose: Specifically recognizes and binds to glucose transporters (such as GLUT1) highly expressed on the surface of various cells (especially tumor cells), enabling receptor-mediated active targeted delivery.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 2000 (Average)
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SMILES
O=C(OC[C@@H](OC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(OCCOC(N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O)=O)=O)(O)=O)CCCCCCCCCCCCCCCCC.[n]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)