N-Acetyl mesalazine
Based on 1 Customer Validation
N-Acetyl mesalazine (N-Acetyl-5-aminosalicylic acid) is the primary intestinal metabolite of 5-Aminosalicylic Acid (HY-15027) and serves as a biomarker for evaluating the efficacy of 5-Aminosalicylic Acid (HY-15027). N-Acetyl mesalazine can scavenge free radicals, reduce DNA base hydroxylation, and ameliorate mucosal inflammation. N-Acetyl mesalazine can be used in the study of diseases such as colitis and colon cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 99.90%
- CAS No.: 51-59-2
- 화학식: C9H9NO4
- 분자량:195.17
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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HY-15027
5-Aminosalicylic AcidEndogenous Metabolite -
HY-66008R
N-Acetyl mesalazine (Standard)Standard of N-Acetyl mesalazine -
HY-113327
1,3,7-Trimethyluric acidCaffeine Metabolite -
HY-15027R
5-Aminosalicylic Acid (Standard)Endogenous Metabolite -
HY-N2736
3′,4′,7-Trihydroxyflavoneflavonoid aglycon compound -
HY-B0373
TioproninAntioxidant -
HY-N0523S
Gallic acid-d2Stable Isotope -
HY-W206016
3-Aminosalicylic acidHydroxybenzoic Acid Compound -
HY-113327R
1,3,7-Trimethyluric acid (Standard)Caffeine Metabolite -
HY-138867S
N-Acetyl(mono)desethylchloroquine-d4Stable Isotope -
HY-G0007S
Omeprazole sulfone-d3Stable Isotope -
HY-B0373R
Tiopronin (Standard)Antioxidant
Biological Activity
제품 설명
In Vitro
Chemical Information
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CAS No. 51-59-2
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Appearance Solid
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분자량 195.17
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화학식 C9H9NO4
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Color Light brown to brown
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SMILES
O=C(O)C1=CC(NC(C)=O)=CC=C1O
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Synonyms
N-Acetyl-5-aminosalicylic acid; N-Acetyl-ASA
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
DMSO : 125 mg/mL (640.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Allgayer H, et al. Modulation of base hydroxylation by bile acids and salicylates in a model of human colonic mucosal DNA: putative implications in colonic cancer. Dig Dis Sci. 1999 Apr;44(4):761-7. [Content Brief]
[2]. Fukuda T, et al. Mucosal concentrations of N-acetyl-5-aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine. J Gastroenterol Hepatol. 2020 Nov;35(11):1878-1885. [Content Brief]
[3]. Willoughby CP, et al. The effect of topical N-acetyl-5-aminosalicylic acid in ulcerative colitis. Scand J Gastroenterol. 1980;15(6):715-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1237 mL | 25.6187 mL | 51.2374 mL | 128.0935 mL |
| 5 mM | 1.0247 mL | 5.1237 mL | 10.2475 mL | 25.6187 mL | |
| 10 mM | 0.5124 mL | 2.5619 mL | 5.1237 mL | 12.8093 mL | |
| 15 mM | 0.3416 mL | 1.7079 mL | 3.4158 mL | 8.5396 mL | |
| 20 mM | 0.2562 mL | 1.2809 mL | 2.5619 mL | 6.4047 mL | |
| 25 mM | 0.2049 mL | 1.0247 mL | 2.0495 mL | 5.1237 mL | |
| 30 mM | 0.1708 mL | 0.8540 mL | 1.7079 mL | 4.2698 mL | |
| 40 mM | 0.1281 mL | 0.6405 mL | 1.2809 mL | 3.2023 mL | |
| 50 mM | 0.1025 mL | 0.5124 mL | 1.0247 mL | 2.5619 mL | |
| 60 mM | 0.0854 mL | 0.4270 mL | 0.8540 mL | 2.1349 mL | |
| 80 mM | 0.0640 mL | 0.3202 mL | 0.6405 mL | 1.6012 mL | |
| 100 mM | 0.0512 mL | 0.2562 mL | 0.5124 mL | 1.2809 mL |
N-Acetyl mesalazine Related Classifications
HY-66008 Related Classifications
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