PFKFB3-IN-2
Based on 1 Customer Validation
PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor. PFKFB3-IN-2 has potential applications in cancer, neurodegenerative diseases, autoimmune diseases, inflammatory diseases, multiple sclerosis, metabolic diseases, angiogenesis inhibition and other diseases.
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- Purity: 99.86%
- CAS No.: 794552-84-4
- 화학식: C14H11NO7S
- 분자량:337.30
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
PFKFB3-IN-2 (page 328, 1159) is a potent PFKFB3 inhibitor that can be used in neuroprotection[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 794552-84-4
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Appearance Solid
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분자량 337.30
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화학식 C14H11NO7S
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Color White to yellow
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SMILES
O=C(C1=CC=CC(S(=O)(NC2=CC=C(C(O)=C2)C(O)=O)=O)=C1)O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 125 mg/mL (370.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9647 mL | 14.8236 mL | 29.6472 mL | 74.1180 mL |
| 5 mM | 0.5929 mL | 2.9647 mL | 5.9294 mL | 14.8236 mL | |
| 10 mM | 0.2965 mL | 1.4824 mL | 2.9647 mL | 7.4118 mL | |
| 15 mM | 0.1976 mL | 0.9882 mL | 1.9765 mL | 4.9412 mL | |
| 20 mM | 0.1482 mL | 0.7412 mL | 1.4824 mL | 3.7059 mL | |
| 25 mM | 0.1186 mL | 0.5929 mL | 1.1859 mL | 2.9647 mL | |
| 30 mM | 0.0988 mL | 0.4941 mL | 0.9882 mL | 2.4706 mL | |
| 40 mM | 0.0741 mL | 0.3706 mL | 0.7412 mL | 1.8529 mL | |
| 50 mM | 0.0593 mL | 0.2965 mL | 0.5929 mL | 1.4824 mL | |
| 60 mM | 0.0494 mL | 0.2471 mL | 0.4941 mL | 1.2353 mL | |
| 80 mM | 0.0371 mL | 0.1853 mL | 0.3706 mL | 0.9265 mL | |
| 100 mM | 0.0296 mL | 0.1482 mL | 0.2965 mL | 0.7412 mL |