Physagulide J
Physagulide J is a kind of withanolides compound that can be isolated from Physalis angulata L.. Many kinds of active ingredients of Physalis angulata L. shows anti-inflammatory and anti-tumor activity.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1496524-09-4
- 화학식: C30H40O7
- 분자량:512.63
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 786-0 | IC50 |
0.39 μM
Compound: 17
|
Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| A498 | IC50 |
0.71 μM
Compound: 17
|
Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| ACHN | IC50 |
0.73 μM
Compound: 17
|
Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| CWR22R | IC50 |
0.9 μM
Compound: 17
|
Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| LNCaP C4-2B | IC50 |
0.49 μM
Compound: 17
|
Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay
|
[PMID: 27295506] |
| RAW264.7 | IC50 |
1.36 μM
Compound: 17
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
|
[PMID: 27295506] |
Chemical Information
-
CAS No. 1496524-09-4
-
분자량 512.63
-
화학식 C30H40O7
-
SMILES
CC(C[C@H]([C@H]([C@H]1C[C@@H]([C@]2([C@@H]3C[C@H]4O[C@]45CC=CC([C@@]5([C@H]3CC[C@@]21C)C)=O)O)OC(C)=O)C)O6)=C(C)C6=O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)