Thalidomide-cyanine 5
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C52H60N6O13S2
- 분자량:1041.20
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
제품 설명
IC50 & Target
[2]|
Cereblon-DDB1 121.6 nM (Kd) |
In Vitro
Thalidomide-cyanine 5 binds to purified human DDB1-human CRBN protein complex with a Kd of 121.6 nM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
분자량 1041.20
-
화학식 C52H60N6O13S2
-
SMILES
O=C1N(C(C2=CC=CC(OCC(NCCCCNC(CCCCCN(/C3=C/C=C/C=C/C4=[N+](C5=C(C4(C)C)C=C(C=C5)S(=O)([O-])=O)CC)C6=C(C3(C)C)C=C(S(=O)(O)=O)C=C6)=O)=O)=C21)=O)C7CCC(NC7=O)=O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Mercer JAM, et al. Continuous evolution of compact protein degradation tags regulated by selective molecular glues. Science. 2024;383(6688):eadk4422. [Content Brief]
[2]. Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014;512(7512):49-53. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thalidomide-cyanine 5 Related Classifications
HY-D3392 Related Classifications
Powered by Bioz