L-Alanine-2-13C,15N
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L-Alanine-2-13C,15Nis the 13C-labeled and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
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- Pureza: 99.99%
- No. CAS: 285977-86-8
- Fòrmula: C213CH715NO2
- Peso molecular:91.08
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Almacenamiento:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 285977-86-8
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Unlabeled Cas 56-41-7
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Appearance Solid
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Peso molecular 91.08
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Fòrmula C213CH715NO2
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Color White to off-white
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SMILES
OC([13C@@H]([15NH2])C)=O
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Synonyms
L-2-Aminopropionic acid-2-13C,15N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvente y solubilidad
H2O : 50 mg/mL (548.97 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Nagashima T, et al. Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine. Sci Rep. 2018 Aug 20;8(1):12427. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 10.9794 mL | 54.8968 mL | 109.7936 mL | 274.4840 mL |
| 5 mM | 2.1959 mL | 10.9794 mL | 21.9587 mL | 54.8968 mL | |
| 10 mM | 1.0979 mL | 5.4897 mL | 10.9794 mL | 27.4484 mL | |
| 15 mM | 0.7320 mL | 3.6598 mL | 7.3196 mL | 18.2989 mL | |
| 20 mM | 0.5490 mL | 2.7448 mL | 5.4897 mL | 13.7242 mL | |
| 25 mM | 0.4392 mL | 2.1959 mL | 4.3917 mL | 10.9794 mL | |
| 30 mM | 0.3660 mL | 1.8299 mL | 3.6598 mL | 9.1495 mL | |
| 40 mM | 0.2745 mL | 1.3724 mL | 2.7448 mL | 6.8621 mL | |
| 50 mM | 0.2196 mL | 1.0979 mL | 2.1959 mL | 5.4897 mL | |
| 60 mM | 0.1830 mL | 0.9149 mL | 1.8299 mL | 4.5747 mL | |
| 80 mM | 0.1372 mL | 0.6862 mL | 1.3724 mL | 3.4310 mL | |
| 100 mM | 0.1098 mL | 0.5490 mL | 1.0979 mL | 2.7448 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.