1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Threonine-13C4,15N

L-Threonine-13C4,15N is the 13C- and 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].

For research use only. We do not sell to patients.

L-Threonine-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N Chemical Structure

L-Threonine-13C4,15N Chemical Structure

CAS No. : 202468-39-1

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Description

L-Threonine-13C4,15N is the 13C- and 15N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

124.08

Formula

13C4H915NO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[13CH3][13C@@H](O)[13C@H]([15NH2])[13C](O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 33.33 mg/mL (268.62 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.0593 mL 40.2966 mL 80.5932 mL
5 mM 1.6119 mL 8.0593 mL 16.1186 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.20%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 8.0593 mL 40.2966 mL 80.5932 mL 201.4829 mL
5 mM 1.6119 mL 8.0593 mL 16.1186 mL 40.2966 mL
10 mM 0.8059 mL 4.0297 mL 8.0593 mL 20.1483 mL
15 mM 0.5373 mL 2.6864 mL 5.3729 mL 13.4322 mL
20 mM 0.4030 mL 2.0148 mL 4.0297 mL 10.0741 mL
25 mM 0.3224 mL 1.6119 mL 3.2237 mL 8.0593 mL
30 mM 0.2686 mL 1.3432 mL 2.6864 mL 6.7161 mL
40 mM 0.2015 mL 1.0074 mL 2.0148 mL 5.0371 mL
50 mM 0.1612 mL 0.8059 mL 1.6119 mL 4.0297 mL
60 mM 0.1343 mL 0.6716 mL 1.3432 mL 3.3580 mL
80 mM 0.1007 mL 0.5037 mL 1.0074 mL 2.5185 mL
100 mM 0.0806 mL 0.4030 mL 0.8059 mL 2.0148 mL
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L-Threonine-13C4,15N Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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L-Threonine-13C4,15N
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