Sphingoid Bases

N-glycine Glucosylsphingosine is formed through the glycinylation of 1-β-D-glucosylsphingosine.

3-Deoxysphingosine is a sphingosine.

Sphinganine-1-phosphate (d20:0) is a sphingosine.

Sphingosine-1-phosphate (d20:1) is a sphingosine.

4E,11Z-Sphingadiene is a sphingosine.

Mito-So is a sphingosine.

Lyso SM (d17:1) is a sphingomyelin.

1-Desoxymethylsphingosine (m17:1) is a sphingosine.

N-Methyl-D-erythro-sphingosine is a sphingosine.

4E,14Z-Sphingadiene is a sphosphingolipid.

Dimethyl Sphingosine-1-Phosphate (d18:1) (ammonium) is a sphingosine.

VPC 01091 is a S1PR3 antagonist.

cis-4-methylsphingosine, a synthetic sphingosine analogue, is a sphingosine-1-phosphate receptor modulator,

N-C24:1-desoxymethylsphingosine is a desoxyMeDHCer,which presents in the mammals.

(S)-3-Keto sphinganine (d18:0) hydrochloride is an intermediate in the biosynthesis of C18-Ceramide (HY-100355).

Safingol hydrochloride is a lyso-sphingolipid PKC (protein kinase C ) inhibitor.

4-Hydroxysphinganine C17 base (D-Ribo-phytosphingosine C17 base), also known as D-ribo-phytosphingosine or PHS, is a crucial compound present in the membranes of fungi, plants, bacteria, marine organisms, and mammalian tissues. It plays a vital role in preserving the structural integrity of membranes, regulating cellular growth, and mediating the heat stress response in yeast. Additionally, PHS serves as a precursor for the synthesis of important lipid mediators such as PHS 1-phosphate, inositol phosphorylceramide, and KRN7000 (the α-anomer of galactosylceramide). Furthermore, this phospholipid promotes keratinocyte differentiation, making it a valuable active ingredient in cosmetic formulations.

DL-threo-Dihydrosphingosine is a extracellular signal-regulated kinase(ERK) signalling cassette inhibitor and is effective against both growth factor- and G-protein-dependent activation of ERK. DL-threo-Dihydrosphingosine inhibits smooth muscle cell proliferation and can be used for study of asthma.

Sphingosine (C22-D-erythro-Sphingosine) is a metabolite of sphingolipid and a pro-Apoptotic signaling messenger. Sphingosine induces apoptosis via Caspase-dependent, mitochondria-dependent and lysosomal affinity detergent pathways, downregulates Bcl-2 and Bcl-xL, and truncates Bid and Bax. Sphingosine is used for cancer research.

Sphinganine-1-phosphate (d17:0) is an ester product.