DL-threo-Dihydrosphingosine
DL-threo-Dihydrosphingosine is a extracellular signal-regulated kinase(ERK) signalling cassette inhibitor and is effective against both growth factor- and G-protein-dependent activation of ERK. DL-threo-Dihydrosphingosine inhibits smooth muscle cell proliferation and can be used for study of asthma.
For research use only. We do not sell to patients.
- CAS No.: 2304-75-8
- Formula: C18H39NO2
- Molecular Weight:301.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2304-75-8
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Molecular Weight 301.51
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Formula C18H39NO2
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SMILES
CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Tolan D, et al. The identification of DL-threo dihydrosphingosine and sphingosine as novel inhibitors of extracellular signal-regulated kinase signalling in airway smooth muscle. Br J Pharmacol. 1996;119(2):185-186. [Content Brief]
[2]. Yoshida K, et al. ELOVL6 deficiency aggravates allergic airway inflammation through the ceramide-S1P pathway in mice. J Allergy Clin Immunol. 2023;151(4):1067-1080.e9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DL-threo-Dihydrosphingosine Related Classifications
HY-112384B Related Classifications
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