Mal-VC-PAB-seco-CBI-PBD dimer
Mal-VC-PAB-seco-CBI-PBD dimer is a highly active drug-linker conjugate. Mal-VC-PAB-seco-CBI-PBD dimer integrates the DNA-damaging effects of two distinct types of compounds: seco-cyclopropabenzindoline (seco-CBI) and pyrrolobenzodiazepine (PBD). Mal-VC-PAB-seco-CBI-PBD dimer is linked via a valine-alanine (VC) linker cleavable by cathepsin B and achieves targeted delivery relying on monoclonal antibodies. Mal-VC-PAB-seco-CBI-PBD dimer is applicable for cancer research.
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- No. CAS: 1661823-95-5
- Fòrmula: C60H72ClN9O11
- Peso molecular:1130.72
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 1661823-95-5
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Peso molecular 1130.72
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Fòrmula C60H72ClN9O11
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SMILES
ClC[C@H]1C2=C(C=C(C3=CC=CC=C32)OCC4=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)C=C4)N(C1)C(CCCCCOC6=C(C=C7C(N=C[C@@]8([H])N(CCC8)C7=O)=C6)OC)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mal-VC-PAB-seco-CBI-PBD dimer Related Classifications
HY-185493 Related Classifications
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