2. GPCR/G Protein Neuronal Signaling Apoptosis
  3. Adrenergic Receptor Apoptosis
  4. Metoprolol Hydrochloride

Metoprolol Hydrochloride is an orally active and selective β1-adrenoceptor antagonist. Metoprolol Hydrochloride exhibits anti-inflammatory, antitumor, and anti-angiogenic properties.

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CAS No. : 56392-18-8

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Top Publications Citing Use of Products

    Metoprolol Hydrochloride purchased from MedChemExpress. Usage Cited in: J Intern Med. 2024 Sep;296(3):291-297.  [Abstract]

    Selective blockers Metoprolol (METO; β1-AR blocker; 10 µmol/L) and ICI118551 (ICI; β2-AR blocker; 10 µmol/L) were used to explore the interactions of the spike protein with β1-AR and β2-AR, respectively.

    Metoprolol Hydrochloride purchased from MedChemExpress. Usage Cited in: J Intern Med. 2024 Sep;296(3):291-297.  [Abstract]

    cAMP accumulation in NMCMs treated with ISO (1 µmol/L) and the spike trimer (10 nmol/L) with or without pretreatment with Metoprolol (10 µmol/L) and ICI118551 (10 µmol/L).

    Metoprolol Hydrochloride purchased from MedChemExpress. Usage Cited in: SSRN. 2024 May 30.

    Quantification of immunofluorescence staining of phosphorylated-GSK3β in NRCFs. The ratio of phosphorylated protein to total protein reflects the activation of signaling pathways. NRCFs were starved for 24h. Mig and Metoprolol (Met: 10 μM) were added ahead for 1h, then ISO was added for 24h. Met was used as positive control.

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    Description

    Metoprolol Hydrochloride is an orally active and selective β1-adrenoceptor antagonist. Metoprolol Hydrochloride exhibits anti-inflammatory, antitumor, and anti-angiogenic properties[1][2][3].

    Molecular Weight

    303.82

    Formula

    C15H26ClNO3
    CAS No.
    SMILES

    OC(CNC(C)C)COC1=CC=C(CCOC)C=C1.Cl
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Metoprolol Hydrochloride Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Metoprolol56392-18-8Adrenergic ReceptorApoptosisBeta ReceptorInhibitorinhibitorinhibit

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