MT-7716 free base
MT-7716 free base (W-212393) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention.
For research use only. We do not sell to patients.
- CAS No.: 610323-32-5
- Formula: C27H28N4O2
- Molecular Weight:440.54
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Opioid Receptor Isoforms
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Biological Activity
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NOP Receptor/ORL1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
1.6 nM
Compound: 1, W-212393
|
Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay
Agonist activity at human cloned NOP receptor expressed in CHO cell membranes after 30 mins by [35S]GTPgammaS binding assay
|
[PMID: 22541041] |
Chemical Information
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CAS No. 610323-32-5
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Molecular Weight 440.54
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Formula C27H28N4O2
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SMILES
O=C(CN(C1=O)C2=CC=CC=C2N1C3CCN(CC3)[C@@H]4CC5=C6C4=CC=CC6=CC=C5)NC
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Synonyms
W-212393
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)