N,N'-Dimethyltrimethyleneurea
Based on 1 Customer Validation
N,N'-Dimethyltrimethyleneurea is an intermediate. N,N'-Dimethyltrimethyleneurea can be used in the preparation of naphthalocyanine compounds (near-infrared absorbing dyes).
For research use only. We do not sell to patients.
- Purity: 99.87%
- CAS No.: 7226-23-5
- Formula: C6H12N2O
- Molecular Weight:128.17
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 7226-23-5
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Appearance Liquid (Density: 1.06 g/cm3)
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Molecular Weight 128.17
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Formula C6H12N2O
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Color Colorless to light yellow
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SMILES
O=C1N(C)CCCN1C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 200 mg/mL (1560.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : ≥ 100 mg/mL (780.21 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (39.01 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (39.01 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Purity & Documentation
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Data Sheet (274 KB)
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SDS (778 KB)
- English - EN (778 KB)
- Français - FR (778 KB)
- Deutsch - DE (778 KB)
- Norwegian - NO (778 KB)
- Español - ES (778 KB)
- Swedish - SV (778 KB)
- Italian - IT (778 KB)
- Korean - KR (778 KB)
- Portuguese - PT (778 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 7.8021 mL | 39.0107 mL | 78.0214 mL | 195.0534 mL |
| 5 mM | 1.5604 mL | 7.8021 mL | 15.6043 mL | 39.0107 mL | |
| 10 mM | 0.7802 mL | 3.9011 mL | 7.8021 mL | 19.5053 mL | |
| 15 mM | 0.5201 mL | 2.6007 mL | 5.2014 mL | 13.0036 mL | |
| 20 mM | 0.3901 mL | 1.9505 mL | 3.9011 mL | 9.7527 mL | |
| 25 mM | 0.3121 mL | 1.5604 mL | 3.1209 mL | 7.8021 mL | |
| 30 mM | 0.2601 mL | 1.3004 mL | 2.6007 mL | 6.5018 mL | |
| 40 mM | 0.1951 mL | 0.9753 mL | 1.9505 mL | 4.8763 mL | |
| 50 mM | 0.1560 mL | 0.7802 mL | 1.5604 mL | 3.9011 mL | |
| 60 mM | 0.1300 mL | 0.6502 mL | 1.3004 mL | 3.2509 mL | |
| 80 mM | 0.0975 mL | 0.4876 mL | 0.9753 mL | 2.4382 mL | |
| 100 mM | 0.0780 mL | 0.3901 mL | 0.7802 mL | 1.9505 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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