N-Oleoyl-L-phenylalanine
Based on 1 Customer Validation
N-Oleoyl-L-phenylalanine is a long-chain N-acyl-L-phenylalanine and also a mitochondrial uncoupler. N-Oleoyl-L-phenylalanine uncouples UCP1-independent respiration in mitochondria, thereby helping to regulate glucose homeostasis. As an endogenous metabolite, the level of N-Oleoyl-L-phenylalanine increases in patients with ulcerative colitis after a high-fat diet. N-Oleoyl-L-phenylalanine can be used in studies related to ulcerative colitis.
For research use only. We do not sell to patients.
- Purity: 99.4%
- CAS No.: 136560-78-6
- Formula: C27H43NO3
- Molecular Weight:429.64
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Storage:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
N-oleoyl-L-phenylalanine uncouples UPC1-independent respiration in mammalian mitochondria and may participate in the regulation of glucose homeostasis[2].
N-oleoyl-L-phenylalanine is an endogenous cell-signaling lipid molecule structurally related to endocannabinoid lipids[2].
N-oleoyl-L-phenylalanine can be directly synthesized via the condensation of oleic acid and L-phenylalanine catalyzed by the mammalian enzyme peptidase M20 domain PM20D1 under physiological pH and substrate concentration conditions. Its production level corresponds to the intracellular concentrations of L-phenylalanine and oleic acid as well as the reaction equilibrium constant (Keq)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 136560-78-6
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Appearance Liquid
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Molecular Weight 429.64
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Formula C27H43NO3
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Color Colorless to light yellow
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (263 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-Oleoyl-L-phenylalanine Related Classifications
HY-138207 Related Classifications
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