136560-78-6
Chemical Structure
N-Oleoyl-L-phenylalanine
- CAS No.: 136560-78-6
- Formula:C27H43NO3
- Molecular Weight:429.64
IUPAC Name: oleoyl-L-phenylalanine
InChIKey: UWKNPULCJWBBDD-JRUKXMRZSA-N
SMILES: OC([C@@H](NC(CCCCCCC/C=C\CCCCCCCC)=O)CC1=CC=CC=C1)=O
Biological Activity: N-Oleoyl-L-phenylalanine is a long-chain N-acyl-L-phenylalanine and also a mitochondrial uncoupler. N-Oleoyl-L-phenylalanine uncouples UCP1-independent respiration in mitochondria, thereby helping to regulate glucose homeostasis. As an endogenous metabolite, the level of N-Oleoyl-L-phenylalanine increases in patients with ulcerative colitis after a high-fat diet. N-Oleoyl-L-phenylalanine can be used in studies related to ulcerative colitis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Oleoyl-L-phenylalanine | 99.4% | N-Oleoyl-L-phenylalanine is a long-chain N-acyl-L-phenylalanine and also a mitochondrial uncoupler. N-Oleoyl-L-phenylalanine uncouples UCP1-independent respiration in mitochondria, thereby helping to regulate glucose homeostasis. As an endogenous metabolite, the level of N-Oleoyl-L-phenylalanine increases in patients with ulcerative colitis after a high-fat diet. N-Oleoyl-L-phenylalanine can be used in studies related to ulcerative colitis. | ||||||||||||||||||||
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References
- [1]. Fritsch J, et al. P063 A comprehensive, multiomic diet intervention study comparing a low fat, high fiber diet to an idealized standard American diet in ulcerative colitis patients[J]. Inflammatory Bowel Diseases, 2020, 26(Supplement_1): S8-S9.
- [2]. Bhandari S, et al. The Biosynthesis and Metabolism of the N-Acylated Aromatic Amino Acids: N-Acylphenylalanine, N-Acyltyrosine, N-Acyltryptophan, and N-Acylhistidine. Front Mol Biosci. 2022;8:801749. Published 2022 Jan 3. [Content Brief]
