NAMPT degrader-3
NAMPT degrader-3 (compound C5) is a NAMPT degrader, depending on VHL- and proteasome manner. NAMPT degrader-3 displays cytotoxicity and inhibits A2780 cells proliferation.
For research use only. We do not sell to patients.
- Formula: C56H74N8O7S
- Molecular Weight:1003.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A2780 | IC50 |
30.6 nM
Compound: C5
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Antiproliferative activity against human A2780 cells assessed as cell growth inhibition
Antiproliferative activity against human A2780 cells assessed as cell growth inhibition
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[PMID: 37369332] |
| HUVEC | IC50 |
0.3 nM
Compound: C5
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Cytotoxicity activity against HUVEC cells assessed as cell growth inhibition
Cytotoxicity activity against HUVEC cells assessed as cell growth inhibition
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[PMID: 37369332] |
Chemical Information
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Molecular Weight 1003.30
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Formula C56H74N8O7S
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SMILES
O=C([C@@H](NC(CCCCCCCNC(C1=CC=C(C(N2CCC(CC2)CCCCNC(/C=C/C3=CC=CN=C3)=O)=O)C=C1)=O)=O)C(C)(C)C)N4C[C@@H](C[C@H]4C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NAMPT degrader-3 Related Classifications
HY-155506 Related Classifications
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