Sirusertib
Sirusertib (WEE1A&Myt1-IN-1) is a dual Wee1A/Myt1 inhibitor, with an IC50 of ≤10 nM against Wee1A and ≤20 nM against Myt1. Sirusertib is applicable for cancer-related research.
For research use only. We do not sell to patients.
- CAS No.: 3066062-53-8
- Formula: C27H29N9O2
- Molecular Weight:511.58
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
In Vitro
Sirusertib (Compound 109) inhibits Wee1A and Myt1 with IC50 values of ≤10 nM and ≤20 nM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
-
CAS No. 3066062-53-8
-
Molecular Weight 511.58
-
Formula C27H29N9O2
-
SMILES
O=C1C2=CN=C(NC3=CC(C=NN4C)=C4C=C3)N=C2N(N1CC=C)C5=NC(OC6CCN(CC6)C)=CC=C5
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sirusertib Related Classifications
HY-188057 Related Classifications
Powered by Bioz