2. Protein Tyrosine Kinase/RTK
  3. c-Met/HGFR
  4. OSI-296

OSI-296 is a potent, oral and selective inhibitor of cMET and RON kinases. OSI-296 shows in vivo efficacy in MKN45 tumor xenografts models and well tolerated.

For research use only. We do not sell to patients.

OSI-296 Chemical Structure

OSI-296 Chemical Structure

CAS No. : 1175296-94-2

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OSI-296 Related Antibodies

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Description

OSI-296 is a potent, oral and selective inhibitor of cMET and RON kinases. OSI-296 shows in vivo efficacy in MKN45 tumor xenografts models and well tolerated[1].

Molecular Weight

465.30

Formula

C21H19Cl2FN4O3
CAS No.
SMILES

O=C(N)N1CC=C(CC1)C2=COC3=C2C=NC(N)=C3O[C@H](C)C4=C(C=CC(F)=C4Cl)Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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OSI-296 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

OSI-2961175296-94-2OSI296OSI 296c-Met/HGFRfuropyridinestyrosine kinase inhibitortumor growth inhibitioncMETRONMKN45Inhibitorinhibitorinhibit

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