1175296-94-2
1175296-94-2
Chemical Structure
OSI-296
- CAS No.: 1175296-94-2
- Formula:C21H19Cl2FN4O3
- Molecular Weight:465.30
IUPAC Name: (R)-4-(6-amino-7-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)furo[3,2-c]pyridin-3-yl)-3,6-dihydropyridine-1(2H)-carboxamide
InChIKey: LVYXERPKYAQGKM-SNVBAGLBSA-N
SMILES: O=C(N)N1CC=C(CC1)C2=COC3=C2C=NC(N)=C3O[C@H](C)C4=C(C=CC(F)=C4Cl)Cl
Biological Activity: OSI-296 is a potent, oral and selective inhibitor of cMET and RON kinases. OSI-296 shows in vivo efficacy in MKN45 tumor xenografts models and well tolerated[1].
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OSI-296 | OSI-296 is a potent, oral and selective inhibitor of cMET and RON kinases. OSI-296 shows in vivo efficacy in MKN45 tumor xenografts models and well tolerated. | |||||||||||||||||||||
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References
Keywords
