- Biochemical Assay Reagents
- Chelators
Chelators

Chelators refer to a class of compounds capable of forming complexes with metal ions. They contain two or more ligands that react with metal ions to form stable chelates. Typically, chelators possess multiple functional groups, such as quaternary ammonium and amino groups, which can encapsulate metal ions within the molecule. This encapsulation reduces the catalytic performance of metal ions, thereby mitigating their influence on reactions.
Chelators are widely used in the fields of pharmaceutical preparations, cosmetics and food to regulate pH values and enhance stability.
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Chelators (148)
- Formula: C10H13N2Na3O8 · xH2O
- Molecular Weight: 376.20
EDTA (Ethylenediaminetetraacetic acid) hydrate sodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). EDTA hydrate sodium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. EDTA hydrate sodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA hydrate sodium can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research.
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- Formula: C16H31N7O5
- Molecular Weight: 401.46
DOTAM-mono-acid is a chelator with DOTAM as its core. DOTAM-mono-acid contains a carboxylic acid group that can be activated to form an amide bond with the N-terminus of a peptide. DOTAM-mono-acid can form peptide conjugates for radiometal labeling.
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- Formula: C23H31N5O7S
- Molecular Weight: 521.59
p-NCS-Bz-NODA-GA is a bifunctional chelator.
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- Formula: C2H3NaO3
- Molecular Weight: 98.03
Sodium glycolate, 98% (Sodium hydroxyacetate, 98%) is an orally active, versatile organic salt. Sodium glycolate, 98% acts as an enzyme activity regulator that increases the activities of glycolate oxidase (GAO) and lactate dehydrogenase (LDH), while reducing the activity of glycolate dehydrogenase (GAD). Sodium glycolate, 98% induces oxalate biosynthesis and causes hyperoxaluria in rats. Sodium glycolate, 98% reduces urinary calcium excretion in male albino rats. Sodium glycolate, 98% can be used in studies related to calcium oxalate urolithiasis and hyperoxaluria.
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- Formula: C10H20N2Na2O12Zn
- Molecular Weight: 471.63
Zn(II)-EDTA (Ethylenediaminetetraacetic acid zinc) disodium tetrahydrate is a coordinating agent. Zn(II)-EDTA disodium tetrahydrate coordinates with Zn2+ to modify its solvated structure, provides pre-synthesized EDTA-Zn complexes that release Zn2+ to repair zinc anode defects under interfacial electric field, adsorbs onto zinc anode surface to block oxygen and water molecules, inhibits corrosion and hydrogen evolution reactions, promotes uniform Zn2+ deposition, suppresses zinc dendrite formation, and modulates the hydrogen bonding network within the electrolyte. Zn(II)-EDTA disodium tetrahydrate acts as an electrolyte additive to enhance reversibility and stability of zinc anodes in aqueous zinc-ion batteries.
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- Formula: C20H33N5O7
- Molecular Weight: 455.51
Butyne-DOTAis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Butyne-DOTA can be used for conjugation of peptides and radionuclides.
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- Formula: Na2HPO3·5H2O
- Molecular Weight: 216.04
Sodium phosphite dibasic pentahydrate, 98% (di-Sodium hydrogen phosphite, 98%) is an inorganic phosphorus source and an alkali metal salt of phosphorous acid. Sodium phosphite dibasic pentahydrate, 98% acts as a catalyst for the butanetetracarboxylic acid-based crosslinking reaction of cotton cellulose.
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- Formula: C16H32N8O4
- Molecular Weight: 400.48
DOTA-amideis a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTA-amide can be used for conjugation of peptides and radionuclides.
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- Formula: C12H32N4O12P4
- Molecular Weight: 548.30
DOTMP is a bifunctional chelator. Bifunctional chelating agents are used to stably link the radiometal to the carrier moiety of the radiopharmaceutical.
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- Formula: C10H18N2O7
- Molecular Weight: 278.26
EDTA-OH is a chelating agent, which forms thermodynamically stable chelates with metal ions like calcium, magnesium, iron, zinc and copper. EDTA-OH exhibits ability of phytoremediation in heavy-metal-contaminated soils. EDTA-OH is able to cross brain-blood barrier.
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- Formula: C10H20MgN2Na2O12
- Molecular Weight: 430.56
Mg(Ⅱ)-EDTA (Ethylenediaminetetraacetic acid magnesium) disodium tetrahydrate is a divalent metal chelator and ferroptosis inducer. Mg (Ⅱ)-EDTA disodium tetrahydrate reduces E-cadherin expression by chelating Ca2+ on the surface of tumor cells, thereby triggering cell dissociation and inducing epithelial-mesenchymal transition (EMT). Mg (Ⅱ)-EDTA disodium tetrahydrate further chelates lysosomal iron to form EDTA-Fe, induces ferroptosis through the Fenton reaction, and synergistically enhances immune responses to inhibit tumor metastasis. Mg (Ⅱ)-EDTA (disodium tetrahydrate) can be used in tumor-related research.
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- Formula: C49H74N6O11
- Molecular Weight: 923.15
Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. Fmoc-L-Lys-mono-amide-DOTA-tris(t-Bu ester) can be used for conjugation of peptides and radionuclides.
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- Formula: B2O3
- Molecular Weight: 69.62
Boric anhydride,99.98% trace metals basis (Boron trioxide,99.98% trace metals basis) is a kind of biochemical reagent.
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- Formula: Al2(SO4)3.16H2O
- Molecular Weight: 630.40
Aluminum sulfate hexadecahydrate is a kind of biochemical reagent.
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- Formula: Zn(CH3CO2)2.2H2O
- Molecular Weight: 219.50
Zinc acetate dihydrate, ACS, 98% (Zinc (II) acetate dihydrate, ACS, 98%) acts as a metal chelator and an intestinal metallothionein inducer. Zinc acetate dihydrate, ACS, 98% induces intestinal metallothionein synthesis and shortens the course of the common cold. Zinc acetate dihydrate, ACS, 98% is applicable to the research of copper metabolism disorder-related diseases, the common cold and Wilson's disease, as well as protein experiments.
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- Formula: C6H12O7.1/2Mg.H2O
- Molecular Weight: 225.68
Magnesium D-gluconate hydrate, 98% is a strong chelating agent that chelates calcium, iron, aluminum, copper, and other heavy metal anions.
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- Formula: C6H12O7.1/2Fe.H2O
- Molecular Weight: 269.01
Iron(II) D-gluconate dihydrate, 98% is used for blood coagulation.
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- Formula: C3H6N2O
- Molecular Weight: 86.09
2-Imidazolidone, 96% is a chelating agent that forms complexes with metal ions, enabling its use in catalytic processes.
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