29932-54-5
Chemical Structure
Mg(Ⅱ)-EDTA disodium tetrahydrate
Synonym(s): Ethylenediaminetetraacetic acid magnesium disodium tetrahydrate
- CAS No.: 29932-54-5
- Formula:C10H20MgN2Na2O12
- Molecular Weight:430.56
InChIKey: NTLBRFLUZXNZAU-UHFFFAOYSA-J
SMILES: O=C1[O-][Mg+2]([N]2(C1)CC3=O)([O-]3)([O-]C4=O)([O-]5)[N](C4)(CC2)CC5=O.O.[Na+].O.O.O.[Na+]
Biological Activity: Mg(Ⅱ)-EDTA (Ethylenediaminetetraacetic acid magnesium) disodium tetrahydrate is a divalent metal chelator and ferroptosis inducer. Mg (Ⅱ)-EDTA disodium tetrahydrate reduces E-cadherin expression by chelating Ca2+ on the surface of tumor cells, thereby triggering cell dissociation and inducing epithelial-mesenchymal transition (EMT). Mg (Ⅱ)-EDTA disodium tetrahydrate further chelates lysosomal iron to form EDTA-Fe, induces ferroptosis through the Fenton reaction, and synergistically enhances immune responses to inhibit tumor metastasis. Mg (Ⅱ)-EDTA (disodium tetrahydrate) can be used in tumor-related research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mg(Ⅱ)-EDTA disodium tetrahydrate | 99.0% | Mg(Ⅱ)-EDTA (Ethylenediaminetetraacetic acid magnesium) disodium tetrahydrate is a divalent metal chelator and ferroptosis inducer. Mg (Ⅱ)-EDTA disodium tetrahydrate reduces E-cadherin expression by chelating Ca2+ on the surface of tumor cells, thereby triggering cell dissociation and inducing epithelial-mesenchymal transition (EMT). Mg (Ⅱ)-EDTA disodium tetrahydrate further chelates lysosomal iron to form EDTA-Fe, induces ferroptosis through the Fenton reaction, and synergistically enhances immune responses to inhibit tumor metastasis. Mg (Ⅱ)-EDTA (disodium tetrahydrate) can be used in tumor-related research. | ||||||||||||||||||||
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