1. MAPK/ERK Pathway
  2. p38 MAPK
  3. p38α inhibitor 3

p38α inhibitor 3 (Comp G7) is a p38α inhibitor that blocks the effectiveness of myoblast differentiation.

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p38α inhibitor 3 Chemical Structure

p38α inhibitor 3 Chemical Structure

CAS No. : 260428-69-1

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Description

p38α inhibitor 3 (Comp G7) is a p38α inhibitor that blocks the effectiveness of myoblast differentiation[1].

Molecular Weight

297.37

Formula

C19H20FNO

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CCC(CC1)CC2=CC=CC=C2)C3=CC=C(C=C3)F

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (420.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3628 mL 16.8141 mL 33.6281 mL
5 mM 0.6726 mL 3.3628 mL 6.7256 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3628 mL 16.8141 mL 33.6281 mL 84.0704 mL
5 mM 0.6726 mL 3.3628 mL 6.7256 mL 16.8141 mL
10 mM 0.3363 mL 1.6814 mL 3.3628 mL 8.4070 mL
15 mM 0.2242 mL 1.1209 mL 2.2419 mL 5.6047 mL
20 mM 0.1681 mL 0.8407 mL 1.6814 mL 4.2035 mL
25 mM 0.1345 mL 0.6726 mL 1.3451 mL 3.3628 mL
30 mM 0.1121 mL 0.5605 mL 1.1209 mL 2.8023 mL
40 mM 0.0841 mL 0.4204 mL 0.8407 mL 2.1018 mL
50 mM 0.0673 mL 0.3363 mL 0.6726 mL 1.6814 mL
60 mM 0.0560 mL 0.2802 mL 0.5605 mL 1.4012 mL
80 mM 0.0420 mL 0.2102 mL 0.4204 mL 1.0509 mL
100 mM 0.0336 mL 0.1681 mL 0.3363 mL 0.8407 mL
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p38α inhibitor 3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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p38α inhibitor 3
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HY-153002
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