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Cat. No.: HY-171301

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p38α MAPK/CK1δ inhibitor-1

p38α MAPK/CK1δ inhibitor-1 (Compound 3) exhibits inhibitory activity against p38α MAPK and CK1δ with IC₅₀s of 0.185 µM and 0.089 µM.

For research use only. We do not sell to patients.

CAS No.: 1572047-84-7
Formula: C₂₄H₁₇FN₆O₂
Molecular Weight:440.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

p38α MAPK/CK1δ inhibitor-1 Chemical Structure

CAS No.: 1572047-84-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

p38α MAPK/CK1δ inhibitor-1 (Compound 3) exhibits inhibitory activity against p38α MAPK and CK1δ with IC₅₀s of 0.185 µM and 0.089 µM^[1].

All p38 MAPK Isoforms :

All Casein Kinase Isoforms :

Chemical Information

CAS No. 1572047-84-7
Molecular Weight 440.43
Formula C₂₄H₁₇FN₆O₂
SMILES

O=C(C1=CC=CC(N2N=NC(C3=NC(C4=CC=C(F)C=C4)=C(N3C)C5=CC=NC=C5)=C2)=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Seerden JP, et al., Synthesis and structure-activity relationships of 4-fluorophenyl-imidazole p38α MAPK, CK1δ and JAK2 kinase inhibitors. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3412-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
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p38α MAPK/CK1δ inhibitor-1

All p38 MAPK Isoforms

All Casein Kinase Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

p38α MAPK/CK1δ inhibitor-1 Related Classifications

HY-171301 Related Classifications

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