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Petosemtamab (FUT8-KO)

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Based on 1 Customer Validation

Petosemtamab (FUT8-KO) is an anti-EGFR and anti-LGR5 monoclonal antibody expressed in CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucosyl loss enhances the ADCC effect of the antibody. Petosemtamab (FUT8-KO) leads to EGFR signaling blockade and receptor degradation in LGR5+ cancer cells. Petosemtamab (FUT8-KO) can be used for research on solid tumors such as head and neck squamous cell carcinoma (HNSCC) and metastatic colorectal cancer (CRC).

For research use only. We do not sell to patients.

  • Purity: 99%
  • Molecular Weight:145.5 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Petosemtamab (FUT8-KO)
  • Experimental Validation Results for Petosemtamab (FUT8-KO)
  • Petosemtamab (FUT8-KO) Chemical Structure
    Petosemtamab (FUT8-KO) Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Other Forms of Petosemtamab (FUT8-KO):

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Top Publications Citing

Use of MCE Products

All EGFR Isoforms

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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Loaded Petosemtamab (FUT8-KO) on ProA biosensor, can bind EGFR Protein, Human (621a.a, CHO, His, HY-P7340) with an affinity constant of 5.043E-09 M as determined in BLI assay.

  • Petosemtamab (FUT8-KO) Chemical Structure
    1/16
  • Petosemtamab (FUT8-KO)
  • Loaded Petosemtamab (FUT8-KO) on ProA biosensor, can bind EGFR Protein, Human (621a.a, CHO, His, HY-P7340) with an affinity constant of 5.043E-09 M as determined in BLI assay.
  • IgG1-kappa