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Petosemtamab

(Synonyms: MCLA 158)
Customer Review

Based on 1 Customer Validation

Petosemtamab (MCLA 158) is an anti- EGFR (Kd: 0.22 nM) and anti-LGR5 (Kd: 0.86 nM) monoclonal antibody (mAb). Petosemtamab leads to EGFR signaling blockade and receptor degradation in LGR5+ cancer cells. Petosemtamab can be used in the research of solid tumors, such as head and neck squamous cell carcinoma (HNSCC), metastatic colorectal cancer (CRC).

For research use only. We do not sell to patients.

  • Purity: 99.94%
  • CAS No.: 2213450-26-9
  • Molecular Weight:145.5 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Petosemtamab
  • Experimental Validation Results for Petosemtamab
  • Experimental Validation Results for Petosemtamab
  • Petosemtamab Chemical Structure
    Petosemtamab Chemical Structure
CAS No.: 2213450-26-9
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized EGFR Protein, Human (621a.a, CHO, His, HY-P7340) can bind Petosemtamab. The EC50 for this effect is 4.45 ng/mL.

  • 1/16

    Immobilized HY-P79308 Lgr5/GPR49 Protein, Human (CHO, hFc) can bind Petosemtamab. The EC50 for this effect is 85 ng/mL.

  • Petosemtamab Chemical Structure
    1/16
  • Petosemtamab
  • Immobilized EGFR Protein, Human (621a.a, CHO, His, HY-P7340) can bind Petosemtamab. The EC50 for this effect is 4.45 ng/mL.
  • Immobilized HY-P79308 Lgr5/GPR49 Protein, Human (CHO, hFc) can bind Petosemtamab. The EC50 for this effect is 85 ng/mL.