Polyvinyl alcohol (Mw 85000-124000, 99+% hydrolyzed)  (Synonyms: PVA (Mw 85000-124000, 99+% hydrolyzed); Poly(Ethenol) (Mw 85000-124000, 99+% hydrolyzed))

Polyvinyl alcohol (Mw 85000-124000, 99+% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 85000-124000 and hydrolytic properties. Polyvinyl alcohol (Mw 85000-124000, 99+% hydrolyzed) forms hydrogels that can be used to simulate digestive organs and lesion models for the training of endoscopic ultrasound (EUS) and endoscopic ultrasound elastography (EUS-E). Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipients^[1][2].

Polyvinyl alcohol has the density and stiffness (Young's modulus) of its hydrogels positively correlated with its molecular weight (MW) and concentration (C), and through regulating its molecular weight, concentration and the number of freeze-thaw cycles, it enables the precise control of the hydrogels’ mechanical properties (e.g., hardness and elasticity), thus mimicking different biological tissues from soft ones (e.g., normal tissues) to rigid ones (e.g., solid tumors)^[1][2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

85000-124000 (Approximately)

(C₂H₄O)n

9002-89-5

Solid

White to off-white

CCC(O)C.[n]

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

• [1]. Galvis-García ES, et al. Experimental model standardizing polyvinyl alcohol hydrogel to simulate endoscopic ultrasound and endoscopic ultrasound-elastography. World J Gastroenterol. 2020 Sep 14;26(34):5169-5180.  [Content Brief]

  [2]. Zhang K, et al. Application of polyvinyl alcohol/chitosan copolymer hydrogels in biomedicine: A review. Int J Biol Macromol. 2023 Jul 1;242(Pt 4):125192.  [Content Brief]