Pomalidomide-C6-O-C5-O-C4-COOH
Based on 1 Customer Validation
Pomalidomide-C6-O-C5-O-C4-COOH is a E3 ligase ligand-linker conjugate comprising a Pomalidomide (HY-10984)-based cereblon ligand and linker. Pomalidomide-C6-O-C5-O-C4-COOH can be used for the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.99%
- CAS No.: 2375774-54-0
- Formula: C29H41N3O8
- Molecular Weight:559.65
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Chemical Information
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CAS No. 2375774-54-0
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Appearance Oil
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Molecular Weight 559.65
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Formula C29H41N3O8
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Color Light yellow to yellow
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SMILES
O=C(O)CCCCOCCCCCOCCCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (178.68 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7868 mL | 8.9342 mL | 17.8683 mL | 44.6708 mL |
| 5 mM | 0.3574 mL | 1.7868 mL | 3.5737 mL | 8.9342 mL | |
| 10 mM | 0.1787 mL | 0.8934 mL | 1.7868 mL | 4.4671 mL | |
| 15 mM | 0.1191 mL | 0.5956 mL | 1.1912 mL | 2.9781 mL | |
| 20 mM | 0.0893 mL | 0.4467 mL | 0.8934 mL | 2.2335 mL | |
| 25 mM | 0.0715 mL | 0.3574 mL | 0.7147 mL | 1.7868 mL | |
| 30 mM | 0.0596 mL | 0.2978 mL | 0.5956 mL | 1.4890 mL | |
| 40 mM | 0.0447 mL | 0.2234 mL | 0.4467 mL | 1.1168 mL | |
| 50 mM | 0.0357 mL | 0.1787 mL | 0.3574 mL | 0.8934 mL | |
| 60 mM | 0.0298 mL | 0.1489 mL | 0.2978 mL | 0.7445 mL | |
| 80 mM | 0.0223 mL | 0.1117 mL | 0.2234 mL | 0.5584 mL | |
| 100 mM | 0.0179 mL | 0.0893 mL | 0.1787 mL | 0.4467 mL |