PROTAC BET Degrader-13
PROTAC BET Degrader-13 (Compound 34) is a TRIM21-based PROTAC (TRIMTAC) degrader targeting BET. PROTAC BET Degrader-13 significantly degrades PML-eGFP-BRD4 fusion protein with a near-complete loss of EGFP+ nuclear puncta with an EC50 of 1.4 μM.
(Pink: BET ligand (HY-13030); Blue: TRIM21 ligand (HY-W1125585); Black: linker).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C47H54ClN9O6S
- Peso molecular:908.51
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Actividad biológica
Chemical Information
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Peso molecular 908.51
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Fòrmula C47H54ClN9O6S
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SMILES
O=C(C[C@H]1N=C(C2=C(N3C(C)=NN=C13)SC=C2C)C4=CC=C(C=C4)Cl)NCCOCCOCCOCc5cc(N6C(C7=CC=CC=C7N=C6CN8CCNC[C@@H]8C)=O)c(OCC)cc5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC BET Degrader-13 Related Classifications
HY-175354 Related Classifications
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