2. Metabolic Enzyme/Protease
  3. MMP
  4. PythiDC

PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents.

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PythiDC

PythiDC 화학구조

CAS No. : 1821370-71-1

사이즈 가격 재고 수량
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg   견적 받기  
200 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

PythiDC Related Antibodies

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제품 설명

PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents[1].

분자량

250.23

화학식

C10H6N2O4S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=C(C2=NC=C(C(O)=O)S2)N=C1)O
선적

Room temperature in continental US; may vary elsewhere.
보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
용액&용해도
In Vitro: 

1 M NaOH : 50 mg/mL (199.82 mM; Need ultrasonic)

DMSO : 4.9 mg/mL (19.58 mM; ultrasonic and warming and adjust pH to 4 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9963 mL 19.9816 mL 39.9632 mL
5 mM 0.7993 mL 3.9963 mL 7.9926 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / 1 M NaOH 1 mM 3.9963 mL 19.9816 mL 39.9632 mL 99.9081 mL
5 mM 0.7993 mL 3.9963 mL 7.9926 mL 19.9816 mL
10 mM 0.3996 mL 1.9982 mL 3.9963 mL 9.9908 mL
15 mM 0.2664 mL 1.3321 mL 2.6642 mL 6.6605 mL
1 M NaOH 20 mM 0.1998 mL 0.9991 mL 1.9982 mL 4.9954 mL
25 mM 0.1599 mL 0.7993 mL 1.5985 mL 3.9963 mL
30 mM 0.1332 mL 0.6661 mL 1.3321 mL 3.3303 mL
40 mM 0.0999 mL 0.4995 mL 0.9991 mL 2.4977 mL
50 mM 0.0799 mL 0.3996 mL 0.7993 mL 1.9982 mL
60 mM 0.0666 mL 0.3330 mL 0.6661 mL 1.6651 mL
80 mM 0.0500 mL 0.2498 mL 0.4995 mL 1.2489 mL
100 mM 0.0400 mL 0.1998 mL 0.3996 mL 0.9991 mL
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PythiDC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PythiDC1821370-71-1MMPMatrix metalloproteinasesprobecollagenantifibroticantimetastaticInhibitorinhibitorinhibit

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상품명:
PythiDC
Cat. No.:
HY-103070
수량:
MCE Japan Authorized Agent:

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