1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Chemokine & Receptors
  4. CC chemokine subfamily
  5. MCP-1/CCL2 Protein, Rat (HEK293, His)

MCP-1/CCL2 Protein, Rat (HEK293, His)

Cat. No.: HY-P7236
Handling Instructions

MCP-1/CCL2 Protein, Rat (HEK293, His) is a small cytokine that belongs to the CC chemokine family.

For research use only. We do not sell to patients.

Protein Expression Service

Recombinant Proteins-MedChemExpress
Size Price Stock Quantity
10 μg $190 In-stock
Estimated Time of Arrival: December 31
50 μg $490 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

* Please select Quantity before adding items.

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MCP-1/CCL2 Protein, Rat (HEK293, His) Related Classifications

  • Technical Parameters

  • Properties

  • Documentation








P14844 (Q24-N148)

Gene ID


rRtMCP-1/CCL2; C-C motif chemokine 2; MCAF; MCP-1; SCYA2
AA Sequence


Molecular Weight

10-15 kDa

Biological Activity
The ED50 is <0.3 μg/mL as measured by CHO-K1/Gα15/rCCR2 cells (human Gα15 and rat CCR2 stably expressed in CHO-K1 cells).

Lyophilized powder.


Lyophilized after extensive dialysis against PBS.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.


It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

Storage & Stability

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.


Room temperature in continental US; may vary elsewhere.


CCL2 is produced by a variety of cell types, either constitutively or after induction by oxidative stress, cytokines, or growth factors. CCL2 is produced by many cell types, including endothelial, fibroblasts, epithelial, smooth muscle, mesangial, astrocytic, monocytic, and microglial cells. CCL2 regulates the migration and infiltration of monocytes, memory T lymphocytes, and natural killer (NK) cells[1]. The chemokine CCL2 and its main chemokine receptor CCR2 have been implicated in the pathogenesis of several different disease processes, including vascular permeability and attraction of immune cells during metastasis, a number of different neurological disorders, autoimmune disease, obesity, and atherosclerosis[2].

  • Reconstitution Calculator

  • Dilution Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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MCP-1/CCL2 Protein, Rat (HEK293, His)
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