RP23618
RP23618 is a non peptidic RANTES antagonist with the IC50 of 3 μM. RP23618 inhibit RANTES-induced chemotaxis of THP-1 cells.
For research use only. We do not sell to patients.
- CAS No.: 207991-30-8
- Formula: C30H35N5O3S2
- Molecular Weight:577.76
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| THP-1 | IC50 |
3 μM
Compound: 1, RP-23618
|
Inhibition of [125I]RANTES binding to THP-1 cell membranes rich in C-C chemokine receptor types 1
Inhibition of [125I]RANTES binding to THP-1 cell membranes rich in C-C chemokine receptor types 1
|
[PMID: 9871539] |
Chemical Information
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CAS No. 207991-30-8
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Molecular Weight 577.76
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Formula C30H35N5O3S2
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SMILES
O=S(C1=CC=C(SC2=C3C=CC=C2)C(N3CCCN4CCC5(N(CNC5=O)C6=CC=CC=C6)CC4)=C1)(N(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)