(S)-Erypoegin K
(S)-Erypoegin K is a potent anticancer agent. (S)-Erypoegin K shows potent anti-proliferative activity against HL-60 cells. (S)-Erypoegin K induces apoptosis.
For research use only. We do not sell to patients.
- CAS No.: 2055053-90-0
- Formula: C20H18O6
- Molecular Weight:354.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| GCIY | IC50 |
0.27 μM
Compound: (S)-EpK
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Cytotoxicity against human GCIY cells assessed as reduction in cell viability measured after 48 hrs by MTS/CellTiter96 aqueous one solution cell proliferation assay
Cytotoxicity against human GCIY cells assessed as reduction in cell viability measured after 48 hrs by MTS/CellTiter96 aqueous one solution cell proliferation assay
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[PMID: 33341500] |
| HL-60 | IC50 |
90 nM
Compound: (S)-EpK
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Antiproliferative activity against human HL60 cells assessed as inhibition of cell viability incubated for 48 hrs by MTS assay
Antiproliferative activity against human HL60 cells assessed as inhibition of cell viability incubated for 48 hrs by MTS assay
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[PMID: 32299660] |
| MKN-1 | IC50 |
0.327 μM
Compound: (S)-EpK
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Cytotoxicity against human MKN-1 cells assessed as reduction in cell viability measured after 48 hrs by MTS/CellTiter96 aqueous one solution cell proliferation assay
Cytotoxicity against human MKN-1 cells assessed as reduction in cell viability measured after 48 hrs by MTS/CellTiter96 aqueous one solution cell proliferation assay
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[PMID: 33341500] |
(S)-Erypoegin K (0-1 µM; 48 h)shows potent anti-proliferative activity against HL-60 cells with an IC50 of 90 nM[1].
(S)-Erypoegin K (0.1, 0.5 µM; 24 h) induces marked activation of caspase-3 and −9 in HL-60 cells in a time- and dose-dependent manner[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2055053-90-0
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Molecular Weight 354.35
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Formula C20H18O6
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SMILES
CC(O)([C@@H]1CC2=C(O1)C=C(C3=C2OC=C(C3=O)C4=CC=C(C=C4)O)O)C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S)-Erypoegin K Related Classifications
HY-N10392 Related Classifications
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