2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. (S)-Glutarimide-amide-Py-piperidine-CHO

(S)-Glutarimide-amide-Py-piperidine-CHO 

Cat. No.: HY-49390 Purity: 99.05%
COA
SDS
Handling Instructions Technical Support

(S)-Glutarimide-amide-Py-piperidine-CHO is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

For research use only. We do not sell to patients.

(S)-Glutarimide-amide-Py-piperidine-CHO

(S)-Glutarimide-amide-Py-piperidine-CHO Chemical Structure

CAS No. : 2649400-06-4

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(S)-Glutarimide-amide-Py-piperidine-CHO Related Antibodies

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Description

(S)-Glutarimide-amide-Py-piperidine-CHO is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

IC50 & Target

Cereblon

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(S)-Glutarimide-amide-Py-piperidine-CHO Related Antibodies
Molecular Weight

344.37

Formula

C17H20N4O4
CAS No.
Appearance

Solid

SMILES

C(N[C@@H]1C(=O)NC(=O)CC1)(=O)C=2C=CC(=CN2)N3CCC(C=O)CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation

Purity: 99.05%

SDS (393 KB)

COA (247 KB) HNMR (136 KB) RP-HPLC (233 KB) LCMS (332 KB)

Handling Instructions (2659 KB)
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(S)-Glutarimide-amide-Py-piperidine-CHO Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-Glutarimide-amide-Py-piperidine-CHO2649400-06-4E3 Ligase Ligand-Linker ConjugatesInhibitorinhibitorinhibit

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