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Cat. No.: HY-49390

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(S)-Glutarimide-amide-Py-piperidine-CHO

(S)-Glutarimide-amide-Py-piperidine-CHO is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

For research use only. We do not sell to patients.

Purity: 99.05%
CAS No.: 2649400-06-4
Formula: C₁₇H₂₀N₄O₄
Molecular Weight:344.37

Storage:

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

(S)-Glutarimide-amide-Py-piperidine-CHO Chemical Structure

CAS No.: 2649400-06-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
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Biological Activity

Description

(S)-Glutarimide-amide-Py-piperidine-CHO is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.

IC₅₀ & Target

Cereblon

All E3 Ligase Ligand-Linker Conjugates Isoforms :

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2649400-06-4
Appearance Solid
Molecular Weight 344.37
Formula C₁₇H₂₀N₄O₄
Color White to off-white
SMILES

C(N[C@@H]1C(=O)NC(=O)CC1)(=O)C=2C=CC(=CN2)N3CCC(C=O)CC3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)