1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. (S,R,S)-AHPC-C6-NH2 hydrochloride

(S,R,S)-AHPC-C6-NH2 hydrochloride (Synonyms: VH032-C6-NH2 hydrochloride)

Cat. No.: HY-136006A
Handling Instructions

(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1.

For research use only. We do not sell to patients.

(S,R,S)-AHPC-C6-NH2 hydrochloride Chemical Structure

(S,R,S)-AHPC-C6-NH2 hydrochloride Chemical Structure

CAS No. : 2360522-76-3

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Description

(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].

IC50 & Target[1]

VHL

 

In Vitro

(S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C5-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader, XF038-161A, example 6, extracted from patent WO2019173516A1[1].

Molecular Weight

594.21

Formula

C₂₉H₄₄ClN₅O₄S

CAS No.

2360522-76-3

SMILES

[H]Cl.O=C(N(C[[email protected]](O)C1)[[email protected]@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[[email protected]](C(C)(C)C)NC(CCCCCCN)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

(S,R,S)-AHPC-C6-NH2VH032-C6-NH2E3 Ligase Ligand-Linker ConjugateAKTdegradationXF038-161APROTACrheumatoid arthritisosteoarthritisCrohn’sdiseaseangiofibromaretinalvascularizationdiabetic retinopathyInhibitorinhibitorinhibit

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(S,R,S)-AHPC-C6-NH2 hydrochloride
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HY-136006A
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