2360522-76-3
Chemical Structure
(S,R,S)-AHPC-C6-NH2 hydrochloride
Synonym(s): VH032-C6-NH2 hydrochloride
- CAS No.: 2360522-76-3
- Formula:C29H44ClN5O4S
- Molecular Weight:594.21
IUPAC Name: (2S,4R)-1-((S)-2-(7-aminoheptanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride
InChIKey: UOVYBJUFEMNLOT-VIXMLYKZSA-N
SMILES: [H]Cl.O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCCN)=O
Biological Activity: (S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].
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(S,R,S)-AHPC-C6-NH2 hydrochloride | (S,R,S)-AHPC-C6-NH2 hydrochloride (VH032-C6-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 hydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1. | |||||||||||||||||||||
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Keywords
