(S,R,S)-AHPC-C6-NH2 dihydrochloride
(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1.
For research use only. We do not sell to patients.
- CAS No.: 2341796-77-6
- Formula: C29H45Cl2N5O4S
- Molecular Weight:630.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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HY-135045
(S,R,S)-AHPC-C4-COOH -
HY-103603B
(S,R,S)-AHPC-PEG2-NH2 dihydrochloride -
HY-103598
(S,R,S)-AHPC-PEG3-N3 -
HY-103601
(S,R,S)-AHPC-PEG4-N3 -
HY-103600
(S,R,S)-AHPC-PEG1-N3 -
HY-103602
(S,R,S)-AHPC-PEG3-NH2 hydrochloride -
HY-103603
(S,R,S)-AHPC-PEG2-NH2 hydrochloride -
HY-136165
(S,R,S)-AHPC-PEG3-propionic acid -
HY-103604
(S,R,S)-AHPC-PEG4-NH2 hydrochloride -
HY-103606
(S,R,S)-AHPC-PEG6-C4-Cl -
HY-103599
(S,R,S)-AHPC-PEG2-N3 -
HY-103607
(S,R,S)-AHPC-PEG2-C4-Cl
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
VHL |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2341796-77-6
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Molecular Weight 630.67
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Formula C29H45Cl2N5O4S
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SMILES
[H]Cl.[H]Cl.O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCCN)=O
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Synonyms
VH032-C6-NH2 dihydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(S,R,S)-AHPC-C6-NH2 dihydrochloride Related Classifications
HY-136006 Related Classifications
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