2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. (S,R,S)-AHPC-C6-NH2 dihydrochloride

(S,R,S)-AHPC-C6-NH2 dihydrochloride  (Synonyms: VH032-C6-NH2 dihydrochloride)

Cat. No.: HY-136006
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(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1.

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(S,R,S)-AHPC-C6-NH2 dihydrochloride

(S,R,S)-AHPC-C6-NH2 dihydrochloride Estructura química

No. CAS : 2341796-77-6

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(S,R,S)-AHPC-C6-NH2 dihydrochloride Related Antibodies

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

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Descripciòn

(S,R,S)-AHPC-C6-NH2 dihydrochloride (VH032-C6-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for AKT PROTAC degrader. (S,R,S)-AHPC-C6-NH2 dihydrochloride is XF038-161A, example 6, extracted from patent WO2019173516A1[1].

IC50 & Target[1]

VHL

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(S,R,S)-AHPC-C6-NH2 dihydrochloride Related Antibodies
Peso molecular

630.67

Fòrmula

C29H45Cl2N5O4S
No. CAS
SMILES

[H]Cl.[H]Cl.O=C(N(C[C@H](O)C1)[C@@H]1C(NCC2=CC=C(C(SC=N3)=C3C)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCCN)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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(S,R,S)-AHPC-C6-NH2 dihydrochloride Related Classifications

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Keywords:

(S,R,S)-AHPC-C6-NH22341796-77-6VH032-C6-NH2E3 Ligase Ligand-Linker ConjugatesAKTdegradationXF038-161APROTACrheumatoid arthritisosteoarthritisCrohn’sdiseaseangiofibromaretinalvascularizationdiabetic retinopathyInhibitorinhibitorinhibit

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(S,R,S)-AHPC-C6-NH2 dihydrochloride
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