(S,S,S)-Icafolin-methyl
Based on 1 Customer Validation
(S,S,S)-Icafolin-methyl is an isomer of Icafolin-methyl (HY-170505). Icafolin-methyl is a herbicide and plant β-tubulin (Microtubule/Tubulin) inhibitor. Icafolin-methyl binds to the β-tubulin region of the Colchicine (HY-16569) binding site, thereby blocking the polymerization of plant tubulin. As a non-selective herbicide, Icafolin-methyl exhibits post-emergence activity against weeds in both cool-season and warm-season cropping systems, including resistant ryegrass and darnel biotypes. Icafolin-methyl can be used for herbicide research.
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 2254813-53-9
- Formula: C18H18F2N2O5
- Molecular Weight:380.34
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 2254813-53-9
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Appearance Solid
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Molecular Weight 380.34
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Formula C18H18F2N2O5
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Color White to off-white
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SMILES
COC([C@@H](OC1)C[C@@H]1NC([C@]2(CC(C3=CC(F)=CC(F)=C3)=NO2)C=C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (262.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (282 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6292 mL | 13.1461 mL | 26.2923 mL | 65.7307 mL |
| 5 mM | 0.5258 mL | 2.6292 mL | 5.2585 mL | 13.1461 mL | |
| 10 mM | 0.2629 mL | 1.3146 mL | 2.6292 mL | 6.5731 mL | |
| 15 mM | 0.1753 mL | 0.8764 mL | 1.7528 mL | 4.3820 mL | |
| 20 mM | 0.1315 mL | 0.6573 mL | 1.3146 mL | 3.2865 mL | |
| 25 mM | 0.1052 mL | 0.5258 mL | 1.0517 mL | 2.6292 mL | |
| 30 mM | 0.0876 mL | 0.4382 mL | 0.8764 mL | 2.1910 mL | |
| 40 mM | 0.0657 mL | 0.3287 mL | 0.6573 mL | 1.6433 mL | |
| 50 mM | 0.0526 mL | 0.2629 mL | 0.5258 mL | 1.3146 mL | |
| 60 mM | 0.0438 mL | 0.2191 mL | 0.4382 mL | 1.0955 mL | |
| 80 mM | 0.0329 mL | 0.1643 mL | 0.3287 mL | 0.8216 mL | |
| 100 mM | 0.0263 mL | 0.1315 mL | 0.2629 mL | 0.6573 mL |